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Decreased platelet membrane fluidity in retinal periphlebitis in Eales' disease.

Sandeep S Saxena, Prachi P Srivastava, Dipak D Kumar, Vinay K VK Khanna, and Prahlad K PK Seth

Ocul Immunol Inflamm 14(2):113-6 (2006) PMID 16597541

Oxidative damage to cellular membranes plays an important role in the pathobiology of tissue injury. Free radical-induced peroxidation of membrane lipid and protein is associated with alterations in cellular, morphological, biochemical, and physical dynamics, which are related to the mobility of lipid molecules. Retinal photoreceptors and platelets have been shown to be an easy target of oxidants because of their high proportion of polyunsaturated fatty acids. This study was undertaken, for the first time, to investigate membrane fluidity in the platelets of patients with Eales' disease.

DOI: 10.1080/09273940600557043
Version: za2963e q8zaa q8zb9 q8zcd q8zd0 q8ze2 q8zf7 q8zgb

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