Growth hormone treatment improves growth and clinical status in prepubertal children with cystic fibrosis: results of a multicenter randomized controlled trial.

doi:10.1210/jc.2006-1101

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Growth hormone treatment improves growth and clinical status in prepubertal children with cystic fibrosis: results of a multicenter randomized controlled trial.

Dana S DS Hardin, Beverley B Adams-Huet, Daniel D Brown, Barbara B Chatfield, Maynard M Dyson, Thomas T Ferkol, Michelle M Howenstine, Claude C Prestidge, Frederick F Royce, Julie J Rice, Dan K DK Seilheimer, Joel J Steelman and Ross R Shepherds J Clin Endocrinol Metab 91(12):4925-9 (2006) PMID 17018651

This multicenter, randomized, controlled, crossover trial of prepubertal children with cystic fibrosis (CF) tests the hypotheses that recombinant human GH (rhGH) treatment 1) improves height, weight, lean mass, and bone content irrespective of baseline measures; 2) improves clinical status and quality of life; and 3) has continued effect after cessation after 1 yr of treatment.

DOI: 10.1210/jc.2006-1101
Version: za2963e q8za0 q8zb6 q8zc2 q8zd8 q8ze2 q8zf5 q8zg3

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Growth hormone treatment improves growth and clinical status in prepubertal children with cystic fibrosis: results of a multicenter randomized controlled trial.

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