Preclinical pharmacology of AL-12182, a new ocular hypotensive 11-oxa prostaglandin analog.
J Ocul Pharmacol Ther 22(5):291-309 (2006) PMID 17076623
The aim of this study was to determine selected in vivo ocular properties of AL-12182 (5,6-dihydro-4,5-didehydro-11-deoxy-11-oxa-16-(3-chlorophenoxy)-omega-tetranor-PGF(2alpha) isopropyl ester) and the in vitro profile of its free acid, AL-12180.
DOI: 10.1089/jop.2006.22.291
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