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Testosterone supplementation of megestrol therapy does not enhance lean tissue accrual in men with human immunodeficiency virus-associated weight loss: a randomized, double-blind, placebo-controlled, multicenter trial.

Kathleen K Mulligan, Robert R Zackin, Jamie H JH Von Roenn, Margaret A MA Chesney, Merrill J MJ Egorin, Fred R FR Sattler, Constance A CA Benson, Tun T Liu, Triin T Umbleja, Sharon S Shriver, Richard J RJ Auchus, Morris M Schambelan, and

J Clin Endocrinol Metab 92(2):563-70 (2007) PMID 17090640

Reduced energy intake is a primary factor in HIV-associated wasting. Megestrol acetate (MA) stimulates appetite and weight gain. However, much of the weight gained is fat, possibly as a result of MA-induced hypogonadism.

DOI: 10.1210/jc.2006-0954
Version: za2963e q8za7 q8zb0 q8zc3 q8zd9 q8zeb q8zf4 q8zg1
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