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Selective targeting of E. coli heat-stable enterotoxin analogs to human colon cancer cells.

Michael F MF Giblin, Gary L GL Sieckman, Lisa D LD Watkinson, Said S Daibes-Figueroa, Timothy J TJ Hoffman, Leonard R LR Forte, and Wynn A WA Volkert

Anticancer Res 26(5A):3243-51 (2006) PMID 17094436

Radiolabeled analogs of the E. coli heat-stable enterotoxin (ST(h)) are currently under study as imaging and therapeutic agents for colorectal cancer. The aim of these studies is to compare in vitro and in vivo characteristics of two novel ST(h) analogs with appended DOTA chelating moieties.

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