Germline mutation in the aryl hydrocarbon receptor interacting protein gene in familial somatotropinoma.

doi:10.1210/jc.2006-2394

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Germline mutation in the aryl hydrocarbon receptor interacting protein gene in familial somatotropinoma.

Rodrigo A RA Toledo, Delmar M DM Lourenço, Bernardo B Liberman, Malebranche B C MB Cunha-Neto, Maria G MG Cavalcanti, Cinthia B CB Moyses, Sergio P A SP Toledo and Patricia L M PL Dahia J Clin Endocrinol Metab 92(5):1934-7 (2007) PMID 17341560

Acromegaly is usually sporadic, but familial cases occur in association with several familial pituitary tumor syndromes. Recently mutations in the aryl hydrocarbon receptor interacting protein (AIP) gene were associated with familial pituitary adenoma predisposition.

DOI: 10.1210/jc.2006-2394
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