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Efficacy and safety evaluation of once-daily OROS hydromorphone in patients with chronic low back pain: a pilot open-label study (DO-127).

Mark Wallace, Roman Skowronski, Sarita Khanna, Iulia Cristina Tudor, and John Thipphawong

Curr Med Res Opin 23(5):981-9 (2007) PMID 17519065

To evaluate the safety, tolerability, and efficacy of once-daily osmotic controlled-release oral delivery system (OROS) hydromorphone in patients with chronic low back pain of moderate-to-severe intensity.

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