Objective: Assisted reproduction techniques can minimize the risk of HIV female contamination when the male partner is HIV-infected. The aim of this study was to investigate the efficiency of sperm washing and intrauterine insemination (IUI) in these couples. Study design: Retrospective comparative study. Eighty-four HIV-1 serodicordant couples underwent 294 IUI. The control group was composed of 90 couples (320 IUI cycles) with donor sperm. Spermatozoa from HIV-1 infected male partner were prepared and tested for HIV-1 according to sperm washing method. Spermatozoa from HIV-1 and donor male were frozen before IUI. IUI were performed after ovarian stimulation. Main outcomes measures were pregnancy rate per cycle and baby take-home rate per couples. Results: Although the pregnancy rate and baby take-home rate were higher in IUI with sperm washing than in IUI using donor sperm (18.0 versus 14.7 and 52.4 versus 41.1, respectively), the differences were not statistically significant. In serodiscordant couples, blood estradiol levels under ovarian stimulation and total motile sperm inseminated were a determining factor in achieving pregnancy. No female HIV-1 contamination occurred. Conclusion: This study demonstrates that sperm washing and IUI are highly effective in enabling serodiscordant couples with an HIV-1 infected male partner to have a child.
The problem of destination accessibility is a vital concern in the
sustainable tourism development in the emerging regions due to the increasing
numbers of tourism business growth in the recent times. Tourism is one of the
potential foreign exchange earning sectors, which place sustainability as on...
More and more large data collections are gathered worldwide in various IT
systems. Many of them possess the networked nature and need to be processed and
analysed as graph structures. Due to their size they require very often usage
of parallel paradigm for efficient computation. Three parallel tech...
We present intriguing hints likely
Suggesting that it is a transient gamma-ray source flaring on short timescales.
If fully confirmed by further studies, the implications stemming are huge, both
Theoretically and observationally, and would add a further extreme
Characteristic to the already extreme...
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