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Comparison of the inflammatory burden of truly asymptomatic carotid atheroma with atherosclerotic plaques contralateral to symptomatic carotid stenosis: an ultra small superparamagnetic iron oxide enhanced magnetic resonance study.

Tjun Y TY Tang, Simon P S SP Howarth, Sam R SR Miller, Martin J MJ Graves, Jean-Marie JM U-King-Im, Rikin A RA Trivedi, Zhi Yong ZY Li, Stewart R SR Walsh, Andrew P AP Brown, Peter J PJ Kirkpatrick, Michael E ME Gaunt, and Jonathan H JH Gillard

J Neurol Neurosurg Psychiatry 78(12):1337-43 (2007) PMID 17578854

Inflammation is a recognised risk factor for the vulnerable atherosclerotic plaque. The aim of this study was to explore whether there is a difference in the degree of magnetic resonance (MR) defined inflammation using ultra small superparamagnetic iron oxide (USPIO) particles within carotid atheroma in completely asymptomatic individuals and the asymptomatic carotid stenosis contralateral to the symptomatic side.

DOI: 10.1136/jnnp.2007.118901
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