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Topotecan vitreous levels after periocular or intravenous delivery in rabbits: an alternative for retinoblastoma chemotherapy.

Angel M AM Carcaboso, Guillermo F GF Bramuglia, Guillermo L GL Chantada, Adriana C AC Fandiño, Diego A DA Chiappetta, Maria T G MT de Davila, Modesto C MC Rubio, and David H DH Abramson

Invest Ophthalmol Vis Sci 48(8):3761-7 (2007) PMID 17652749

To determine the extent and the mechanism by which topotecan, a candidate agent for the treatment of retinoblastoma, gains access to the vitreous when administered by periocular injection or intravenous infusion.

DOI: 10.1167/iovs.06-1152
Version: za2963e q8zae q8zb0 q8zcc q8zd8 q8zea q8zfc q8zgd

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