Advanced search×

Transducing particles of Staphylococcus aureus pathogenicity island SaPI1 are comprised of helper phage-encoded proteins.

Sandra M SM Tallent, Timothy B TB Langston, Richard G RG Moran, and Gail E GE Christie

J Bacteriol 189(20):7520-4 (2007) PMID 17693489 PMCID 2168463

The relationship between the composition of SaPI1 transducing particles and those of helper phage 80alpha was investigated by direct comparison of virion proteins. Twelve virion proteins were identified by sodium dodecyl sulfate-polyacrylamide gel electrophoresis and mass spectrometry; all were present in both 80alpha and SaPI1 virions, and all were encoded by 80alpha. No SaPI1-encoded proteins were detected. This confirms the prediction that SaPI1 is encapsidated in a virion assembled from helper phage-encoded proteins.

Referenced by 1 articles

DOI: 10.1128/JB.00738-07
Version: za2963e q8za6 q8zb3 q8zc3 q8zdc q8ze0 q8zf5 q8zgb
Buy PDF

Similar articles you may find interesting…

  1. Highly Potent Inhibitors of Quorum Sensing in Staphylococcus aureus Revealed Through a Systematic Synthetic Study of the Group-III Autoinduc...
    Yftah Tal-Gan, Danielle M Stacy, and Helen E Blackwell

    J Am Chem Soc (2013) PMID 23647400

    We seek to expand this set of chemical probes, and report herein the first design, synthesis, and biological testing of AIP-III mimetics. A set of non-native peptides was identified that can inhibit all four of the AgrC receptors (I-IV) with picomolar IC50 values in reporter strains. These analogs a...
    Buy PDF
  2. Phosphorylation-dependent conformational changes and domain rearrangements in Staphylococcus aureus VraR activation.
    Paul G Leonard, Dasantila Golemi-Kotra, and Ann M Stock

    Proc Natl Acad Sci U S A (2013) PMID 23650349

    Staphylococcus aureus VraR, a vancomycin-resistance-associated response regulator, activates a cell-wall-stress stimulon in response to antibiotics that inhibit cell wall formation. X-ray crystal structures of VraR in both unphosphorylated and beryllofluoride-activated states have be...
    Buy PDF
  3. Transmission of methicillin-resistant staphylococcus aureus in the long term care facilities in Hong Kong.
    Vincent Cc Cheng, Josepha Wm Tai, and Kwok-Yung Yuen

    BMC Infect Dis 13(1):205 (2013) PMID 23641974

    Our data suggest that MRSA transmission was more serious in LTCFs than in hospitals. Infection control should be focused on LTCFs in order to reduce the burden of MRSA carriers in healthcare settings....
    PDF not found