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World disparities in risk definition and management of retinoblastoma: a report from the International Retinoblastoma Staging Working Group.

Guillermo L GL Chantada, François F Doz, Manuela M Orjuela, Ibrahim I Qaddoumi, Rita S RS Sitorus, Tomas T Kepak, Anna A Furmanchuk, Mauricio M Castellanos, Tarun T Sharma, Patricia P Chevez-Barrios, Carlos C Rodriguez-Galindo, and

Pediatr Blood Cancer 50(3):692-4 (2008) PMID 18059037

Following from the publication of the International Retinoblastoma Staging System, an open internet discussion group was created at the www.cure4kids.org resource. The results of a survey distributed among participants are discussed. Although most patients with retinoblastoma were treated under prospective protocols, there was a wide variation in the definition of risk criteria and in the criteria for giving adjuvant chemotherapy following enucleation. Definition of high-risk histological features and the criteria for use of adjuvant therapy will be standardized in future studies. Internet meetings are a valuable mechanism for enabling participation from under-resourced countries in the development of cooperative studies.

DOI: 10.1002/pbc.21427
Version: za2963e q8zab q8zb6 q8zcf q8zd9 q8zef q8zff q8zg5
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