World disparities in risk definition and management of retinoblastoma: a report from the International Retinoblastoma Staging Working Group.
Pediatr Blood Cancer 50(3):692-4 (2008) PMID 18059037
Following from the publication of the International Retinoblastoma Staging System, an open internet discussion group was created at the www.cure4kids.org resource. The results of a survey distributed among participants are discussed. Although most patients with retinoblastoma were treated under prospective protocols, there was a wide variation in the definition of risk criteria and in the criteria for giving adjuvant chemotherapy following enucleation. Definition of high-risk histological features and the criteria for use of adjuvant therapy will be standardized in future studies. Internet meetings are a valuable mechanism for enabling participation from under-resourced countries in the development of cooperative studies.
DOI: 10.1002/pbc.21427
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