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The MATRICS Consensus Cognitive Battery, part 1: test selection, reliability, and validity.

Keith H KH Nuechterlein, Michael F MF Green, Robert S RS Kern, Lyle E LE Baade, Deanna M DM Barch, Jonathan D JD Cohen, Susan S Essock, Wayne S WS Fenton, Frederick J FJ Frese, James M JM Gold, Terry T Goldberg, Robert K RK Heaton, Richard S E RS Keefe, Helena H Kraemer, Raquelle R Mesholam-Gately, Larry J LJ Seidman, Ellen E Stover, Daniel R DR Weinberger, Alexander S AS Young, Steven S Zalcman, and Stephen R SR Marder

Am J Psychiatry 165(2):203-13 (2008) PMID 18172019

The lack of an accepted standard for measuring cognitive change in schizophrenia has been a major obstacle to regulatory approval of cognition-enhancing treatments. A primary mandate of the National Institute of Mental Health's Measurement and Treatment Research to Improve Cognition in Schizophrenia (MATRICS) initiative was to develop a consensus cognitive battery for clinical trials of cognition-enhancing treatments for schizophrenia through a broadly based scientific evaluation of measures.

DOI: 10.1176/appi.ajp.2007.07010042
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