SMAP29 congeners demonstrate activity against oral bacteria and reduced toxicity against oral keratinocytes.

doi:10.1111/j.1399-302X.2007.00389.x

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SMAP29 congeners demonstrate activity against oral bacteria and reduced toxicity against oral keratinocytes.

P L PL Weistroffer, S S Joly, R R Srikantha, B F BF Tack, K A KA Brogden and J M JM Guthmiller Oral Microbiol Immunol 23(2):89-95 (2008) PMID 18279175

Cathelicidins are antimicrobial peptides found in epithelial and mucosal tissues as well as the secondary granules of neutrophils. SMAP29, a sheep cathelicidin, has differential antimicrobial properties against various pathogens, including periodontal organisms. The purpose of this study was to evaluate the antimicrobial properties and cytotoxicity of SMAP29, SMAP28, and three congeners (SMAP18A, SMAP18D, and SMAP14A).

DOI: 10.1111/j.1399-302X.2007.00389.x
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SMAP29 congeners demonstrate activity against oral bacteria and reduced toxicity against oral keratinocytes.

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