Antiangiogenic properties of fasudil, a potent Rho-Kinase inhibitor.

doi:10.1007/s10384-007-0487-5

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Antiangiogenic properties of fasudil, a potent Rho-Kinase inhibitor.

Yasuaki Y Hata, Muneki M Miura, Shintaro S Nakao, Shuhei S Kawahara, Takeshi T Kita and Tatsuro T Ishibashi Jpn J Ophthalmol 52(1):16-23 (2008) PMID 18369695

Vascular endothelial growth factor (VEGF) plays a pivotal role in pathological angiogenesis. In this study, we addressed the therapeutic potential of fasudil, a potent Rho-kinase inhibitor, for VEGF-elicited angiogenesis and also for the intracellular signalings induced by VEGF.

DOI: 10.1007/s10384-007-0487-5
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