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Heme oxygenase-1 induction attenuates corneal inflammation and accelerates wound healing after epithelial injury.

Kiran Patil, Lars Bellner, Giuseppe Cullaro, Katherine H Gotlinger, Michael W Dunn, and Michal Laniado Schwartzman

Invest Ophthalmol Vis Sci 49(8):3379-86 (2008) PMID 18441305

Heme oxygenase (HO) is considered a fundamental endogenous immunomodulatory, cytoprotective, and anti-inflammatory system. This protective function is primarily ascribed to the inducible HO-1. The authors examined the effect of HO-1 induction on corneal inflammation and wound healing in mice undergoing epithelial injury.

DOI: 10.1167/iovs.07-1515
Version: za2963e q8za6 q8zbd q8zc9 q8zd1 q8zee q8zf0 q8zg2
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