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Expression of a recombinant protein immunochemically equivalent to the major Anisakis simplex allergen Ani s 1.

I I Ibarrola, M C MC Arilla, M D MD Herrero, M I MI Esteban, A A Martínez, and J A JA Asturias

J Investig Allergol Clin Immunol 18(2):78-83 (2008) PMID 18447135

Anisakis simplex is a nematode which can parasitize humans, producing anisakiasis and can induce immunoglobulin-(Ig)-E-mediated allergic symptoms. Parasite recombinant proteins, such as the major allergen Ani s 1, may be useful tools to avoid misdiagnosis of A simplex allergy due to cross-reactivity when whole parasite extracts are used.

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