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Proteomic analysis of the hyaloid vascular system regression during ocular development.

Elena E Albè, Jin-Hong JH Chang, Nathalie F NF Azar, Alexander R AR Ivanov, and Dimitri T DT Azar

J Proteome Res 7(11):4904-13 (2008) PMID 18841878

We describe a proteomic approach to investigate the differential protein expression patterns and identify the physiologically relevant angiogenic and antiangiogenic factors involved in the hyaloid vascular system regression. Differentially expressed proteins were identified using two-dimensional gel electrophoresis followed by nanoflow chromatography coupled with tandem mass spectrometry. These proteins are expected to provide insight as to their function in the early maintenance and eventual regression of the hyaloid vascular system.

DOI: 10.1021/pr800551m
Version: za2963e q8za2 q8zb3 q8zcb q8zdf q8ze1 q8zf5 q8zge
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