Advanced search×

A comparison of the efficacy of doramectin, closantel and levamisole in the treatment of the 'oriental eye fluke', Philophthalmus gralli, in commercially reared ostriches (Struthio camelus).

S S Mukaratirwa, M M Chimbwanda, N N Matekwe, and E E Matenga

J S Afr Vet Assoc 79(2):101-3 (2008) PMID 18846856

Commercially reared ostriches at Msengi farm situated in the Chinhoyi area of Mashonaland West province in Zimbabwe were found to be infected with the 'oriental eye fluke', Philopthalmus gralli, in 2001. This was the ist record of the fluke in Zimbabwe. Trials were conducted to identify a suitable drug for the treatment of this fluke. A total of 12 ostriches confirmed to be infected with the fluke through clinical examination of the eyes and identification of the fluke were randomly divided into 3 equal groups, with each group receiving a different treatment protocol. The 3 drugs used were doramectin, levamisole and closantel. Each of the drugs was used in combination with chloramphenicol as an eye ointment. Levamisole was administered topically into the eye whereas doramectin and closantel were administered parenterally as an intramuscular injection. The results indicated a positive response in levamisole-treated birds but there were no noticeable responses to doramectin and closantel treatments.

Version: za2963e q8za6 q8zb9 q8zcf q8zdf q8ze4 q8zf8 q8zgb

Similar articles you may find interesting…

  1. Aspergillus fumigatus-Induced IL-22 Is Not Restricted to a Specific Th Cell Subset and Is Dependent on Complement Receptor 3.
    Mark S Gresnigt, Katharina L Becker, and Frank L van de Veerdonk

    J Immunol (2013) PMID 23645883

    We demonstrate that A. fumigatus induces Th1 and Th17 subsets in human PBMCs. Moreover, we show that the cytokine IL-22 is not restricted to a specific Th subset, in contrast to IL-17A. The pattern recognition and cytokine pathways that skew these Aspergillus-induced Th cell responses are TLR4- and...
  2. Extra domain-A fibronectin is necessary for the development of nasal remodeling in chronic allergen-induced rhinitis.
    Nir Hirshoren, Martin Kohan, and Neville Berkman

    Ann Allergy Asthma Immunol 110(5):322-7 (2013) PMID 23622001

    Extra domain A-containing fibronectin (EDA-FN) is necessary for the development of allergen-induced lower airway fibrosis. The pathogenesis of fibrosis in allergic rhinitis has not been well studied. To determine whether EDA-fibronectin is necessary for the developmen...
  3. Foxc2 induces Wnt4 and Bmp4 expression during muscle regeneration and osteogenesis.
    M C Gozo, P-J Aspuria, and S Orsulic

    Cell Death Differ (2013) PMID 23645207

    We present a novel role for the transcription factor Forkhead box protein C2 (Foxc2) in regulating proliferation and preventing premature differentiation of activated muscle satellite cells. We demonstrate that Foxc2 expression is upregulated early in activated mouse muscle satellite cells and then...