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A human apolipoprotein E mimetic peptide effectively inhibits HSV-1 TK-positive and TK-negative acute epithelial keratitis in rabbits.

Partha S Bhattacharjee, Donna M Neumann, and James M Hill

Curr Eye Res 34(2):99-102 (2009) PMID 19219680

To compare the antiviral effect of a peptide derived from human apolipoprotein E (1% apoEdp) with 1% trifluorothymidine against HSV-1 thymidine kinase (TK)-positive (HSV-1 McKrae) and with 3% foscarnet against HSV-1 TK-negative (KOS background) in the rabbit eye model of acute HSV-1 epithelial keratitis.

DOI: 10.1080/02713680802647662
Version: za2963e q8za6 q8zbf q8zcb q8zd7 q8ze8 q8zf2 q8zg7
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