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Hepatotoxicity Associated with Long- versus Short-Course HIV-Prophylactic Nevirapine Use

June M McKoy, Charles L Bennett, Marc H Scheetz, Virginia Differding, Kevin L Chandler, Kimberly K Scarsi, Paul R Yarnold, Sarah Sutton, Frank Palella, Stuart Johnson, Eniola Obadina, Dennis W Raisch, and Jorge P Parada

Drug Saf 32(2):147-158 (2009) PMID 19236121

The antiretroviral nevirapine can cause severe hepatotoxicity when used 'off-label' for preventing mother-to-child HIV transmission (PMTCT), newborn post-exposure prophylaxis and for pre- and post-exposure prophylaxis among non-HIV-infected individuals. We describe the incidence of hepatotoxicity with short- versus long-course nevirapine-containing regimens in these groups.

DOI: 10.2165/00002018-200932020-00007
Version: za2963e q8zac q8zbd q8zca q8zda q8zef q8zf9 q8zg8
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