APOE genotype modulates the effect of serum calcium levels on cognitive function in old age.

doi:10.1212/01.wnl.0000343852.10018.24

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APOE genotype modulates the effect of serum calcium levels on cognitive function in old age.

P P van Vliet, A M AM Oleksik, S P SP Mooijaart, A J M AJ de Craen and R G J RG Westendorp crossref 72(9):821-8 3 Mar 2009 PMID 19255409

The APOE genotype and serum calcium levels have both been associated with cognitive impairment. Animal studies have shown variation in apoE isoforms to play a critical role in intraneuronal calcium homeostasis, but the contribution of this interaction to cognitive function in man is unknown. Here, we studied whether the APOE genotype modulates the association between serum calcium levels and cognition.

DOI: 10.1212/01.wnl.0000343852.10018.24
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APOE genotype modulates the effect of serum calcium levels on cognitive function in old age.

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