Advanced search×

Production of peptide antifungal antibiotic and biocontrol activity of Bacillus subtilis.

Ajay A Kumar, Pragati P Saini, and J N JN Shrivastava

Indian J Exp Biol 47(1):57-62 (2009) PMID 19317353

Among different bacterial cultures, a potent Bacillus subtilis MTCC-8114 was isolated from garden soil samples which showed 16 and 14 mm inhibition zones by spot inoculation method and 24 and 22 mm inhibition zones by well agar diffusion method against test fungi i.e. Microsporum fulvum and Trichophyton species. Among four media tested, the maximum growth and antibiotic production was found in trypticase soya broth (TSB) medium at 37 degrees C, pH-7 and 48 h of incubation. The Rf value (0.64) by Thin Layer Chromatography (TLC) technique and UV and FTIR spectral data of the active antifungal compound, indicated that the isolated compound belongs to peptide antifungal antibiotic group. MIC value of antifungal antibiotic was 135 and 145 microg/ml.

Version: za2963e q8za8 q8zb0 q8zc3 q8zd4 q8ze4 q8zfb q8zg5
PDF not found

Similar articles you may find interesting…

  1. Evaluation of Bamboo Shoot Peptide Preparation with ACE Inhibitory and Antioxidant Ability from By-products of Canned Bamboo Shoots.
    Lianliang Liu, Lingyi Liu, and Ying Zhang

    J Agric Food Chem (2013) PMID 23647018

    In this paper, aqueous extract fractions (AEBS) from by-products during the processing of canned bamboo shoots, including boiled water, filled liquid and squeezed juice, were obtained then by molecular weight cutoff membranes of 5 KDa and marcoporous resin DA201-C treatment. The enri...
    Buy PDF
  2. Isolation and characterization of a rare waterborne lytic phage of Salmonella enterica serovar Paratyphi B.
    Sangeeta S Ahiwale, Ashok V Bankar, and B P Kapadnis

    Can J Microbiol 59(5):318-23 (2013) PMID 23647344

    A lytic phage of Salmonella serovar Paratyphi B, named φSPB, was isolated from surface waters of the Pavana River in India. Phage φSPB is a member of the Podoviridae family and is morphologically similar to the 7-11 phages of the C3 morphotype of tailed phages, characterized by a v...
    Buy PDF
  3. Platforms for antibiotic discovery.
    Kim Lewis

    Nat Rev Drug Discov 12(5):371-87 (2013) PMID 23629505

    The spread of resistant bacteria, leading to untreatable infections, is a major public health threat but the pace of antibiotic discovery to combat these pathogens has slowed down. Most antibiotics were originally isolated by screening soil-derived actinomycetes during the golden era...
    Buy PDF