Correlates of individual differences in compensatory nicotine self-administration in rats following a decrease in nicotine unit dose.

Psychopharmacology (Berl) 205(4):599-611 (2009) PMID 19475400

The ability of tobacco harm reduction strategies to produce significant reductions in toxin exposure is limited by compensatory increases in smoking behavior. Characterizing factors contributing to the marked individual variability in compensation may be useful for understanding this phenomenon and assessing the feasibility of harm reduction interventions.

DOI: 10.1007/s00213-009-1567-7
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