Advanced search×

Discoid lupus erythematosus in a patient with scleroderma and hepatitis C virus infection.

Mami Yamamoto, Toshiyuki Yamamoto, and Ryoji Tsuboi

Rheumatol Int 30(7):969-71 (2010) PMID 19543731

A 49-year-old Japanese woman presented with discoid lupus erythematosus (DLE) on the face. The presence of Raynaud's phenomenon, swollen fingers, a high anti-nuclear antibody titer, and the results of a biopsy revealed limited-type systemic sclerosis (lSSc). The association of SSc with DLE is rare, although some single case reports have been published in Japan. Our patient was positive for hepatitis C virus infection. Racial predisposition and immune imbalance are proposed to have played a role in the development of these lesions in our case.

DOI: 10.1007/s00296-009-1009-1
Version: za2963e q8zaa q8zb0 q8zc6 q8zd4 q8zeb q8zf1 q8zga
Buy PDF

Similar articles you may find interesting…

  1. Decreased serum interleukin 27 in Brazilian systemic lupus erythematosus patients.
    Angela Luzia Branco Pinto Duarte, Andréa Tavares Dantas, and Maira Galdino da Rocha Pitta

    Mol Biol Rep (2013) PMID 23645091

    The immunological role of interleukin 27 has been reported in various inflammatory diseases, but its importance in systemic lupus erythematosus pathogenesis is not completely established. The aim of this study was to evaluate serum levels of IL-27 in SLE patients and its correlation...
    Buy PDF
  2. Sex-specific differences in the relationship between the single-nucleotide polymorphism rs2298804 of FCER1A and the susceptibility to system...
    J Yang, M-M Lu, and D-Q Ye

    Clin Exp Dermatol 38(4):410-6 (2013) PMID 23621092

    We also found a stronger association of the FCER1A exon SNP, rs2298804 (A/G), in females (OR = 0.42; 95%CI 0.34-0.53; P < 0.04). G-allele carriers are less likely to develop SLE than A-allele carriers. Although we did not find any...
    Buy PDF
  3. Effect of gender on clinical presentation in systemic lupus erythematosus.
    Grainne Murphy and David Isenberg

    Rheumatology (Oxford) (2013) PMID 23641038

    We sought to explore through a detailed literature review whether gender exerts an influence on the clinical presentation and outcome of SLE. We found that males experience less of the typical mucocutaneous and musculoskeletal symptoms commonly present at diagnosis in women. On the other hand, there...
    Buy PDF