A versatile route to the tulearin class of macrolactones: synthesis of a stereoisomer of tulearin A.
Org Lett 11(15):3282-5 (2009) PMID 19555117 PMCID PMC2736336
A versatile synthetic approach to the tulearin class of macrolactones has been developed and deployed to make a stereoisomer of tulearin A. The knowledge gained about structure and synthesis will expedite the assignment of the stereostructure of this new anticancer agent.
DOI: 10.1021/ol900936t
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