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Differential cytokine expression by human dendritic cells in response to different Porphyromonas gingivalis capsular serotypes.

Rolando Vernal, Rubén León, Augusto Silva, Arie J van Winkelhoff, Jose A Garcia-Sanz, and Mariano Sanz

J Clin Periodontol 36(10):823-9 (2009) PMID 19682172

Capsular polysaccharides play an important role in the virulence of Gram-positive and Gram-negative bacteria. In Porphyromonas gingivalis, six serotypes have been described based on capsular antigenicity and its pathogenicity has been correlated both in vitro and in animal models. This study aimed to investigate the differential response of human dendritic cells (DCs) when stimulated with different P. gingivalis capsular serotypes.

DOI: 10.1111/j.1600-051X.2009.01462.x
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