Advanced search×

Distinct mechanisms are utilized to induce stress sensor gadd45b by different stress stimuli

Steven D Zumbrun, Barbara Hoffman, and Dan A Liebermann

J Cell Biochem 108(5):1220-1231 (2009) PMID 19834918

DOI: 10.1002/jcb.22354
Version: za2963e q8za4 q8zb0 q8zc3 q8zd7 q8ze2 q8zf5 q8zg7

Similar articles you may find interesting…

  1. Gadd45a functions as a promoter or suppressor of breast cancer dependent on the oncogenic stress.
    J S Tront, Y Huang, ... D A Liebermann

    Cancer Res 70(23):9671-81 (2010) PMID 21098706 PMCID PMC3199142

    We reported that the stress sensor Gadd45a gene functions as a tumor suppressor in Ras-driven breast tumorigenesis via increasing JNK-mediated apoptosis and p38-mediated senescence. In contrast, here, we show that Gadd45a promotes Myc-driven breast cancer by negatively regulating MMP10 via GSK3 β/...
    View PDF
  2. Gadd45 modulation of intrinsic and extrinsic stress responses in myeloid cells
    Barbara Hoffman and Dan A Liebermann

    J Cell Physiol 218(1):26-31 (2009) PMID 18780287

    Gadd45 proteins modulate signaling in response to physiological and environmental stressors. Expression of gadd45 genes is rapidly induced by different stressors, including differentiation-inducing cytokines and genotoxic stress. Induction of gadd45 genes at the onset of myeloid differentiation sugg...
  3. TOR and ageing: a complex pathway for a complex process.
    Mark A MA McCormick, Shih-Yin SY Tsai, and Brian K BK Kennedy

    Philos Trans R Soc Lond B Biol Sci 366(1561):17-27 (2011) PMID 21115526

    We address downstream targets of mTOR signalling and their possible links to ageing. We also briefly cover other ageing genes identified by comparing worms and yeast, addressing the likelihood that their mammalian counterparts will affect longevity....
    View PDF