Coupling factor B affects the morphology of mitochondria.
J Bioenerg Biomembr 42(1):29-35 (2010) PMID 20069349
Ectopic expression of coupling factor B in animal cells resulted in altered mitochondrial morphology. Cells expressing factor B fused to green fluorescent protein (GFP) contained fragmented, balloon-shaped or thinned, filamentous mitochondria, terminating at one end with balloon-like structures. Ultrastructural analysis using transmission electron microscopy revealed changes in the organization of mitochondrial cristae in cells expressing factor B-GFP fusion protein.
DOI: 10.1007/s10863-009-9263-1
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