The aim of the current study was to investigate the possibility of increasing the maximal tolerated dose (MTD) of a tumor-selective radiolabeled antibody when radioimmunotherapy (RIT) is combined with extracorporeal depletion of radioimmunoconjugates from the circulation. Furthermore, the authors evaluated whether this increase in dose improved the therapeutic effect on solid manifest tumors in an immunocompetent animal model.
We report the discovery of a comet-like tail on asteroid (3200) Phaethon when
Imaged at optical wavelengths near perihelion. In both 2009 and 2012, the tail
Appears >=350" (2.5x10^8 m) in length and extends approximately in the
Projected anti-solar direction. We interpret the tail as being caused by...
This paper used qualitative methods to explore experiences of men who have sex with men and female sex workers in Nairobi and Mtwapa, Kenya, who used oral pre-exposure prophylaxis (PrEP) for HIV prevention as part of a four-month trial of safety, acceptability and adherence. Fifty-on...
We say that $P$ is $P'$-partially
Testable with $q$ queries if there exists an algorithm that distinguishes, with
High probability, inputs in $P'$ from inputs $\epsilon$-far from $P$ by using
$q$ queries. There are natural properties that require many queries to test,
But can be partitioned into a s...
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