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Intraventricular amphotericin for absidiomycosis in an immunocompetent child.

L L Y Tsung, X L Zhu, W C W Chu, D T F Sun, K L Cheung, and T F Leung

Hong Kong Med J 16(2):137-40 (2010) PMID 20354249

Brain abscesses are uncommon in children. We report a 3-year-old, previously healthy and immunocompetent boy, with an Absidia brain abscess. He presented with decreased sensorium and status epilepticus. The brain abscess was detected using cranial computed tomography and magnetic resonance imaging, and the diagnosis was confirmed with pus and brain tissue cultures. The patient responded to surgical drainage with concomitant intravenous and intraventricular amphotericin B.

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