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Nitric oxide and downstream second messenger cGMP and cAMP enhance adipogenesis in primary human preadipocytes.

Karsten K Hemmrich, Caroline C Gummersbach, Nora Emilie NE Paul, Daniela D Goy, Christoph V CV Suschek, Klaus-Dietrich KD Kröncke, and Norbert N Pallua

Audio, Transactions of the IRE Profession... 12(4):547-53 (2010) PMID 20370354

Obesity is correlated with chronic low-grade inflammation. Thus the induction of inflammation could be used to stimulate adipose tissue formation in tissue-engineering approaches. As nitric oxide (NO) is a key regulator of inflammation, we investigated the effect of NO and its downstream signaling molecule guanosine 3',5'-cyclic monophosphate (cGMP) as well as adenosine 3',5'-cyclic monophosphate (cAMP) on preadipocytes in vitro.

DOI: 10.3109/14653241003695042
Version: za2963e q8za3 q8zb3 q8zc6 q8zd6 q8ze7 q8zfd q8zgb
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