The effect of different doses of ascorbic acid on the absorptive functions of the gut has been investigated in chicks. The study describes evidence for the existence of a H+/glycine symport system in chick intestinal brush border, because in sodium-free conditions acidification of the apical medium with ascorbic acid causes a dose-dependent stimulation of glycine absorption. Under the above circumstances, potassium acts as a non-essential activator of H+-dependence glycine cotransport. Our results also suggest that glycine uptake is stimulated in a lesser degree by inward sodium gradient. Ascorbic acid stimulation of glycine uptake from K+- free sodium abundant media was diminished, when the dietary level of ascorbic acid was increased to 2000 mg in 1 kg of food. This may result from conformational change in the Na(-)-dependent glycine transporter protein that lowers glycine binding site affinity induced by the over-acidification of the gut lumen. In addition, there was a possible competition between sodium-dependent glycine and ascorbic acid transporters for sodium.
HSS administration attenuated heart failure-induced kidney dysfunction as indicated by improvement in both glomerular and tubular defects, a finding with important clinical implications. HSS modulated the expression of tubular proteins involved in regulation of water and electrolyte homeostasis....
We show how a high throughput, high spectral resolution
Instrument like the X-ray Integral Field Unit (X-IFU) on Athena+ will allow us
To address these questions by determining the physical parameters (ionization
State, density, temperature, abundances, velocities, geometry, etc.) of the
We collect and review works which treat two-dimensional electron gases in
Quantum wells (mostly GaAs/GaAlAs heterostructures) in the presence of
Quantizing magnetic fields as open systems in contact with outside reservoirs.
If a reservoir is sufficiently large, it pins the Fermi level to a certain
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