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Human CD34+ cells in experimental myocardial infarction: long-term survival, sustained functional improvement, and mechanism of action.

Jingxiong J Wang, Sui S Zhang, Brian B Rabinovich, Luc L Bidaut, Suren S Soghomonyan, Mian M MM Alauddin, James A JA Bankson, Elizabeth E Shpall, James T JT Willerson, Juri G JG Gelovani, and Edward T H ET Yeh

Circ Res 106(12):1904-11 (2010) PMID 20448213 PMCID PMC2908245

Human CD34(+) cells have been used in clinical trials for treatment of myocardial infarction (MI). However, it is unknown how long the CD34(+) cells persist in hearts, whether the improvement in cardiac function is sustained, or what are the underlying mechanisms.

DOI: 10.1161/CIRCRESAHA.110.221762
Version: za2963e q8za5 q8zbe q8zc5 q8zd8 q8ze7 q8zf0 q8zgf
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