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Acute kidney injury and cardiovascular outcomes in acute severe hypertension.

Lynda A Szczech, Christopher B Granger, Joseph F Dasta, Alpesh Amin, W Frank Peacock, Peter A McCullough, John W Devlin, Matthew R Weir, Jason N Katz, Frederick A Anderson, Allison Wyman, Joseph Varon, and Studying the Treatment of Acute Hypertension Investigators

Circulation 121(20):2183-91 (2010) PMID 20458014

Little is known about the association of kidney dysfunction and outcome in acute severe hypertension. This study aimed to measure the association between baseline chronic kidney disease (estimated glomerular filtration rate), acute kidney injury (AKI, decrease in estimated glomerular filtration rate > or =25% from baseline) and outcome in patients hospitalized with acute severe hypertension.

DOI: 10.1161/CIRCULATIONAHA.109.896597
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