Advanced search×

Genetic linkage of serum homocysteine in Dominican families: the Family Study of Stroke Risk and Carotid Atherosclerosis.

David D Della-Morte, Ashley A Beecham, Tatjana T Rundek, Susan S Slifer, Bernadette B Boden-Albala, Mark S MS McClendon, Susan H SH Blanton, and Ralph L RL Sacco

Stroke 41(7):1356-62 (2010) PMID 20489178 PMCID PMC2914470

Homocysteine levels are determined by genetic and environmental factors. Several studies have linked high plasma levels of total homocysteine to the increased risk of cardiovascular disease, stroke, and many other conditions. However, the exact mechanism of documented and novel total homocysteine quantitative trait loci to that risk is unknown.

DOI: 10.1161/STROKEAHA.109.573626
Version: za2963e q8za4 q8zb4 q8zc2 q8zde q8ze9 q8zfa q8zgf
View PDF

Similar articles you may find interesting…

  1. Functional Characterization of Fission Yeast Transcription Factors by Overexpression Analysis.
    Lianne Vachon, Justin Wood, and Gordon Chua

    Genetics (2013) PMID 23695302

    We systematically overexpressed 99 transcription factor genes with the nmt1 promoter and found that 64 transcription factor genes exhibited reduced fitness when ectopically expressed. Cell cycle defects were also often observed. We further investigated three uncharacterized transcription factor gene...
  2. Estradiol Production by the Bidder's Organ of the Toad Rhinella arenarum (Amphibia, Anura). Seasonal Variations in Plasma Estradiol.
    María Florencia Scaia, Eleonora Regueira, and Nora Raquel Ceballos

    J Exp Zool A Ecol Genet Physiol (2013) PMID 23650243

    In bufonids, the Bidder's organ (BO), located in the anterior pole of the testis, is sometimes referred to as a rudimentary ovary because of the presence of previtellogenic follicles. In males of Rhinella arenarum it has been demonstrated that some follicles are vitellogenic and also...
  3. Mutations in ALDH1A3 Cause Microphthalmia.
    Mohammed A Aldahmesh, Arif O Khan, and Fowzan S Alkuraya

    Clin Genet (2013) PMID 23646827

    We identified another homozygous variant in two of the 10 probands with microphthalmiawe specifically screened for mutations in ALDH1A3. Interestingly, the other branch of the original family was found to segregate anophthalmia/syndactyly with a novel homozygous SMOC1 variant.Our data support the ve...