We explore an approach for studying epistasis
In humans using a Drosophila melanogaster model of neonatal diabetes mellitus.
Expression of mutant preproinsulin, hINSC96Y, in the eye imaginal disc mimics
The human disease activating conserved cell stress response pathways leading to
Cell death and re...
We consider a mathematical
Model of two diseases spreading through a single population, where infection
With one disease is dependent on prior infection with the other. We solve
Exactly for the sizes of the outbreaks of both diseases in the limit of large
Population size, along with the complete pha...
We analyze multi-step pathways from different systems
And show that ignoring memory has profound consequences for community detection
And ranking as well as for epidemic spreading. Specifically, memoryless
Dynamics on networks understate the effect of communities and exaggerate the
Effect of highly...
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