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Lipid peroxidation and antioxidant enzyme activities in erythrocytes of type 2 diabetic patients.

Atip A Likidlilid, Natchai N Patchanans, Thavatchai T Peerapatdit, and Charn C Sriratanasathavorn

J Med Assoc Thai 93(6):682-93 (2010) PMID 20572373

Although diabetes mellitus (DM) patients are claimed to be under oxidative stress because of prolonged exposure to hyperglycemia, the influence of glycemic control and cardiovascular complication in diabetes on oxidative stress parameters has not been fully studied. The present study aimed to investigate lipid peroxidation end product (malondialdehyde, MDA) and antioxidant enzymes in fairly controlled type 2 DM (fasting plasma glucose [FPG] < or = 180 mg/dl) or type 2 DM complicated with coronary heart disease (CHD) and poorly controlled type 2 DM (FPG > 180 mg/dl) in comparison to a normal healthy group (FPG < 110 mg/dl).

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