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Nitrogen-bound diazeniumdiolated amidines.

Debanjan Biswas, Jeffrey R Deschamps, Larry K Keefer, and Joseph A Hrabie

Chem Commun (Camb) 46(31):5799-801 (2010) PMID 20589293

In contrast to amidines bearing ionizable alpha-CH bonds, which react with nitric oxide (NO) to add diazeniumdiolate groups at their alpha-carbons, benzamidine forms an N-bound diazeniumdiolate that can be further derivatized at the other amidine nitrogen and/or the terminal oxygen to form caged NO compounds as potential NO prodrugs.

DOI: 10.1039/c0cc00849d
Version: za2963e q8za5 q8zb6 q8zc0 q8zd7 q8zeb q8zf3 q8zg0
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