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The plant cannabinoid Delta9-tetrahydrocannabivarin can decrease signs of inflammation and inflammatory pain in mice.

Daniele D Bolognini, Barbara B Costa, Sabatino S Maione, Francesca F Comelli, Pietro P Marini, Vincenzo V Di Marzo, Daniela D Parolaro, Ruth A RA Ross, Lisa A LA Gauson, Maria G MG Cascio, and Roger G RG Pertwee

Br J Pharmacol 160(3):677-87 (2010) PMID 20590571 PMCID PMC2931567

The phytocannabinoid, Delta(9)-tetrahydrocannabivarin (THCV), can block cannabinoid CB(1) receptors. This investigation explored its ability to activate CB(2) receptors, there being evidence that combined CB(2) activation/CB(1) blockade would ameliorate certain disorders.

DOI: 10.1111/j.1476-5381.2010.00756.x
Version: za2963e q8za9 q8zb6 q8zc0 q8zd7 q8ze6 q8zfb q8zgf
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