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Intensification of a failing regimen with zidovudine may cause sustained virologic suppression in the presence of resensitising mutations including K65R

Journal of Infection 61(4):346 (2010) PMID 20600301

Objectives The reverse transcriptase (RT)-mutation K65R limits further therapeutic options and has been selected by unfavorable RT-combinations, e.g. tenofovir in combination with abacavir and/or didanosine.

DOI: 10.1016/j.jinf.2010.06.008