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Astrocytic damage is far more severe than demyelination in NMO: a clinical CSF biomarker study.

R Takano, T Misu, T Takahashi, S Sato, K Fujihara, and Y Itoyama

Neurology 75(3):208-16 (2010) PMID 20644148

Loss of aquaporin 4 and glial fibrillary acidic protein (GFAP) with necrosis and demyelination is a prominent pathologic feature of neuromyelitis optica (NMO). However, the clinicopathologic significance of astrocytic damage and its relation with demyelination are unknown.

DOI: 10.1212/WNL.0b013e3181e2414b
Version: za2963e q8zac q8zb3 q8zc4 q8zdb q8zee q8zf4 q8zg1

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