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In vivo electrical conductivity across critical nerve gaps using poly(3,4-ethylenedioxythiophene)-coated neural interfaces.

Brent M Egeland, Melanie G Urbanchek, Antonio Peramo, Sarah M Richardson-Burns, David C Martin, Daryl R Kipke, William M Kuzon, and Paul S Cederna

Plast Reconstr Surg 126(6):1865-73 (2010) PMID 20700080

Bionic limbs require sensitive, durable, and physiologically relevant bidirectional control interfaces. Modern central nervous system interfacing is high risk, low fidelity, and failure prone. Peripheral nervous system interfaces will mitigate this risk and increase fidelity by greatly simplifying signal interpretation and delivery. This study evaluates in vivo relevance of a hybrid peripheral nervous system interface consisting of biological acellular muscle scaffolds made electrically conductive using poly(3,4-ethylenedioxythiophene).

DOI: 10.1097/PRS.0b013e3181f61848
Version: za2963e q8za1 q8zb4 q8zc9 q8zd0 q8zed q8zf6 q8zgb

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