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Serum N-glycome biomarker for monitoring development of DENA-induced hepatocellular carcinoma in rat.

Meng M Fang, Sylviane S Dewaele, Yun-Peng YP Zhao, Peter P Stärkel, Valerie V Vanhooren, Yue-Ming YM Chen, Xin X Ji, Ming M Luo, Bao-Mu BM Sun, Yves Y Horsmans, Anne A Dell, Stuart M SM Haslam, Paola P Grassi, Claude C Libert, Chun-Fang CF Gao, and Cuiying Chitty CC Chen

Mol Cancer (2010) PMID 20704698

There is a demand for serum markers for the routine assessment of the progression of liver cancer. We previously found that serum N-linked sugar chains are altered in hepatocellular carcinoma (HCC). Here, we studied glycomic alterations during development of HCC in a rat model.

DOI: 10.1186/1476-4598-9-215
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