Advanced search×

Induced Domain Formation in Endocytic Invagination, Lipid Sorting, and Scission

Ludger Johannes and Satyajit Mayor

Cell 142(4):4 (2010) PMID 20723749

Lipid segregation occurs in biological membranes, but how this plays into cellular processes like endocytosis has been unclear. Here, we discuss how the active or passive induction of lipid-protein domain formation in membranes can alter membrane mechanics and thus affect processes such as the generation of curvature, the scission of buds and tubules, and lipid sorting.

Copyright © 2010 Elsevier Ltd. All rights reserved.

DOI: 10.1016/j.cell.2010.08.007
Version: za2963e q8za9 q8zb1 q8zcd q8zd6 q8ze8 q8zfc q8zg2

Similar articles you may find interesting…

  1. Erratum to: Discovery of LY2457546: a multi-targeted anti-angiogenic kinase inhibitor with a novel spectrum of activity and exquisite potenc...
    A Schneeberger, M Mandler, ... W Schmidt

    Invest New Drugs 30(3):1270-1 (2012) PMID 21597891

    View PDF
  2. Targeted cell-cell interactions by DNA nanoscaffold-templated multivalent bispecific aptamers.
    Xiaowei Liu, Hao Yan, ... Yung Chang

    Small 7(12):1673-82 (2011) PMID 21538862

  3. Nuclear cGMP-dependent kinase regulates gene expression via activity-dependent recruitment of a conserved histone deacetylase complex.
    Yan Y Hao, Ningyi N Xu, ... Ho Yi HY Mak

    PLoS Genet 7(5):e1002065 (2011) PMID 21573134

    We study how EGL-4, the Caenorhabditis elegans PKG ortholog, modulates foraging behavior and egg-laying and seeks the downstream effectors of EGL-4 activity. Using a combination of unbiased forward genetic screen and proteomic analysis, we have identified a conserved SAEG-1/SAEG-2/HDA-2 histone deac...
    View PDF