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Associations of primary and secondary organic aerosols with airway and systemic inflammation in an elderly panel cohort.

Ralph J RJ Delfino, Norbert N Staimer, Thomas T Tjoa, Mohammad M Arhami, Andrea A Polidori, Daniel L DL Gillen, Steven C SC George, Martin M MM Shafer, James J JJ Schauer, and Constantinos C Sioutas

Audio, Transactions of the IRE Professio... 21(6):892-902 (2010) PMID 20811287

Exposure-response information about particulate air-pollution constituents is needed to protect sensitive populations. Particulate matter 2.5 mm (PM2.5) components may induce oxidative stress through reactive-oxygen-species generation, including primary organics from combustion sources and secondary organics from photochemically oxidized volatile organic compounds. We evaluated differences in airway versus systemic inflammatory responses to primary versus secondary organic particle components, particle size fractions, and the potential of particles to induce cellular production of reactive oxygen species.

DOI: 10.1097/EDE.0b013e3181f20e6c
Version: za2963e q8zae q8zb2 q8zc4 q8zd3 q8ze2 q8zf4 q8zga

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