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First-line chemotherapy with capecitabine and temozolomide in patients with metastatic pancreatic endocrine carcinomas.

Jonathan R Strosberg, Robert L Fine, Junsung Choi, Aejaz Nasir, Domenico Coppola, Dung-Tsa Chen, James Helm, and Larry Kvols

Cancer 117(2):268-75 (2011) PMID 20824724

Temozolomide is an active agent in metastatic pancreatic endocrine carcinomas. In vitro data indicate that the combination of capecitabine and temozolomide is synergistic for induction of apoptosis in neuroendocrine tumor cell lines. The authors retrospectively evaluated the efficacy of capecitabine and temozolomide in 30 patients with metastatic pancreatic endocrine carcinomas to assess response rate, progression free survival (PFS), and overall survival (OS).

Referenced by 1 articles

DOI: 10.1002/cncr.25425
Version: za2963e q8za9 q8zbb q8zcf q8zd5 q8ze9 q8zfc q8zg7

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