Site-specific photochemical RNA editing.

Chemical Communications 46(40):7545 (2010) PMID 20848024

Photo-induced artificial RNA editing was demonstrated using photo-reactive oligonucleotides containing 3-cyanovinylcarbazole nucleoside. This non-enzymatic and sequence-specific methodology will make a major contribution to the elucidation of RNA functions including non-coding RNAs and to the development of drugs based on sequence-specific RNA editing.

DOI: 10.1039/c0cc03151h