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Organ culture of the trigeminal ganglion induces enhanced expression of calcitonin gene-related peptide via activation of extracellular signal-regulated protein kinase 1/2.

János J Tajti, Anikó A Kuris, László L Vécsei, Cang-Bao CB Xu, and Lars L Edvinsson

Audio, Transactions of the IRE Profession... 31(1):95-105 (2011) PMID 20851839

Clinical and experimental studies have revealed a central role of calcitonin gene-related peptide (CGRP) in primary headaches. The role of extracellular signal-regulated kinase 1 and 2 (ERK1/2) in neuronal and glial cell expression of CGRP- immunoreactivity (-ir) in rat trigeminal ganglia was studied with an organ culture method.

DOI: 10.1177/0333102410382796
Version: za2963e q8zad q8zbe q8zc4 q8zd9 q8ze7 q8zfe q8zg7

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