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A large-scale, consortium-based genomewide association study of asthma.

Miriam F MF Moffatt, Ivo G IG Gut, Florence F Demenais, David P DP Strachan, Emmanuelle E Bouzigon, Simon S Heath, Erika E von Mutius, Martin M Farrall, Mark M Lathrop, William O C M WO Cookson, and

Audio, Transactions of the IRE Profess... 363(13):1211-21 (2010) PMID 20860503

Susceptibility to asthma is influenced by genes and environment; implicated genes may indicate pathways for therapeutic intervention. Genetic risk factors may be useful in identifying subtypes of asthma and determining whether intermediate phenotypes, such as elevation of the total serum IgE level, are causally linked to disease.

DOI: 10.1056/NEJMoa0906312
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